| Product Name | Rabbit anti-CRKL Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen |
The immunogen for Anti-CRKL antibody is: synthetic peptide directed towards the middle region of Human CRKL |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CRKL |
|---|---|
| Gene Synonyms |
-
|
| Gene Summary |
CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
|
| Molecular Weight(MW) | 34kDa |
| Sequence | 303 amino acids |
| Entrez Gene | 1399 |
|---|---|
| SwissProt ID | P46109 |
| Protein Accession | NP_005198 |
Titration: 1.0 ug/ml
Positive Control: K562 Whole Cell
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |