ATF-2 (phospho Ser472) Antibody
如果您對該產(chǎn)品感興趣的話,可以
產(chǎn)品名稱: ATF-2 (phospho Ser472) Antibody
產(chǎn)品型號:
產(chǎn)品展商: immunoclone
產(chǎn)品文檔: 無相關文檔
簡單介紹
ATF-2 (phospho Ser472) Antibody迅速增長的產(chǎn)品線包括一抗、二抗、**測定及細胞檢測試劑盒、蛋白/多肽、激動劑/拮抗劑/活化劑/抑制劑及裂解物等。ATF-2 (phospho Ser472) Antibody嚴格的質(zhì)量控制和驗證實驗包括各種不同的應用：WB、細胞**熒光、**組化、流式細胞術、ELISA、CHIP、IP和peptide array。
ATF-2 (phospho Ser472) Antibody
的詳細介紹
ATF-2 (phospho Ser472) AntibodyProduct Profile
|
Product Name
|
ATF-2 (phospho Ser472) Antibody
|
|
Antibody Type
|
Primary Antibodies
|
|
Product description
|
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.1) Maekawa T., EMBO J. 8:2023-2028(1989).
More
|
|
Immunogen
|
ATF-2 (phospho Ser472) antibody was raised against a peptide sequence around phosphorylation site of Serine 472 (E-A-V (p)-A-T) derived from Human ATF-2.
|
ATF-2 (phospho Ser472) AntibodyKey Feature
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Host Species
|
Rabbit
|
|
Tested Applications
|
IHC
|
|
Species Reactivity
|
HumanMouseRat
|
|
Concentration
|
1mg/ml
|
|
Purification
|
Affinity purified
|
ATF-2 (phospho Ser472) AntibodyTarget Information
|
Gene Symbol
|
ATF2
|
|
Alternative Names
|
Activating 2
ATF2
cAMP response element binding protein CRE- BP1
CREB2
HB16
More
|
|
Molecular Weight(MW)
|
54 kDa
|
|
Tissue Specificity
|
The antibody detects endogenous levels of ATF-2 only when phosphorylated at serine 472.
|
ATF-2 (phospho Ser472) AntibodyDatabase Links
|
Entrez Gene
|
1386
|
|
Protein Accession
|
NP_001243019.1
|
ATF-2 (phospho Ser472) AntibodyApplication
-
Application
Immunohistochemical analysis of paraffin-embedded human brain tissue using ATF-2 (Phospho-Ser472) antibody (left) or the same antibody preincubated with blocking peptide (right).
Additional Information
|
Form
|
Liquid
|
|
Storage Instructions
|
Store antibody at -20?C for up to one year.
|
|
Storage Buffer
|
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
|
